Depression with dysphoria may need two drug types

‘Findings from a small study suggest that combining an antidepressant with an anticonvulsive drug, a type of drug normally used to treat epilepsy, may be an effective treatment for patients with depression plus dysphoric mood, such as anger or hostility.

A link between depression and anger was first made decades ago, but only in recent years have studies investigated this association and possible treatments, Dr. Massimo Pasquini, from University “La Sapienza” of Rome, and colleagues note in Clinical Practice and Epidemiology in Mental Health, a BioMed Central journal.

In fact, depression plus anger or aggression is almost as common as depression with anxiety, the researchers point out.’

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